Continuing Reassessment of the Risks of Erythropoiesis-Stimulating Agents in Patients with Cancer
نویسندگان
چکیده
منابع مشابه
Continuing reassessment of the risks of erythropoiesis-stimulating agents in patients with cancer.
PURPOSE Erythropoiesis-stimulating agents (ESA) are approved for the treatment of anemia in patients with nonmyeloid malignancies whose anemia is due to the effect of concomitantly administered chemotherapy. Since the 1993 approval of epoetin alfa in patients with cancer, the risk of thrombovascular events, decreased survival, and poorer tumor control have been increasingly recognized. The risk...
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15 صفحه اولErythropoiesis-stimulating agents: benefits and risks in supportive care of cancer
Anemia, already common in cancer patients, is often exacerbated by chemotherapy. Cancer patients who are anemic have been shown to have a blunted response for production of endogenous erythropoietin growth factor. This anemia can be corrected with exogenous erythropoietin growth factors, of which three available are worldwide: epoetin alfa, epoetin beta, and darbepoetin alfa. Collectively, thes...
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ژورنال
عنوان ژورنال: Clinical Cancer Research
سال: 2008
ISSN: 1078-0432,1557-3265
DOI: 10.1158/1078-0432.ccr-07-1872